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About Priligy

Premature ejaculation

Studies suggest premature ejaculation (PE) affects up to 30% of men. Only about 10% of these men seek medical help. It is an under-detected and under-treated medical condition.

The causes of PE are multiple, although significant physical disease is not likely to be the reason. Stress and psychological factors are more likely to play a big part.

PE typically has the following features:

• Ejaculatory latency time (time from vaginal penetration to ejaculation) of less than 2 minutes
• Lack of control over ejaculation
• Negative personal consequences related to the condition

Priligy

The active ingredient in Priligy is dapoxetine. It works by increasing the levels of a chemical in the brain called serotonin. Increases in serotonin levels, in turn, delay ejaculation.

After a single tablet, Priligy will reach maximum levels in 1 to 3 hours, and only 5% will still be in the circulation after 24 hours.

Priligy was originally researched as an SSRI (Selective serotonin reuptake inhibitor) antidepressant, but its short action time made it unsuitable. However, some men taking similar antidepressants complained of delayed ejaculation as a side effect, and Priligy was further investigated and developed as a medication for men with premature ejaculation. Priligy does not work by affecting mood, but by working on the serotonin nerve pathways it slows the time to ejaculation.

Taking Priligy tablets

Priligy tablets are for men 18 to 64 years only. Priligy tablets are not licensed for use in older men.

The starting dose is one 30mg tablet 1 to 3 hours before intercourse. The dose can be increased to one 60mg tablet, as required, providing the 30mg dose has been well tolerated (no significant side effects are experienced).

Priligy tablets can be taken with or without food. Tablets should be swallowed whole with a glass of water. Do not drink grapefruit juice in the 24 hours before taking Priligy.

Do not take daily on a regular basis, or repeat a dose within 24 hours.

Low blood pressure

Priligy can, in some men, cause a reduction in blood pressure with dizziness and even blackouts. Men who feel lightheaded should sit with their head between their knees or lie down until symptoms resolve. They should take no further tablets without consulting a doctor. Increasing from a 30mg tablet to a 60mg would be inadvisable.

Cautions for Priligy tablets

Some men with underlying medical conditions should not take Priligy, without first consulting their doctor. These include men with any of the following:

• History of low blood pressure and symptoms caused by falls in blood pressure, such as dizziness and blackouts when standing up.
• Heart disease.
• Significant liver disease.
• Kidney disease.
• Susceptibility to angle closure glaucoma (a rare form of glaucoma).
• Bleeding or blood clotting problems.
• Epilepsy.
• Other sexual problem, e.g. erectile dysfunction.
• Severe lactose intolerance.

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